Unbinding of Retinoic Acid from its Receptor Studied by Steered Molecular Dynamics
نویسندگان
چکیده
منابع مشابه
Unbinding of retinoic acid from its receptor studied by steered molecular dynamics.
Retinoic acid receptor (RAR) is a ligand-dependent transcription factor that regulates the expression of genes involved in cell growth, differentiation, and development. Binding of the retinoic acid hormone to RAR is accompanied by conformational changes in the protein which induce transactivation or transrepression of the target genes. In this paper we present a study of the hormone binding/un...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1999
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(99)77188-2